A white blood cell policeman, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.
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🔍 Search on JustWatch →The director doesn't push the comedy pedal — lets the scene develop at its own pace. The comedic effect arises naturally, without cuing the audience.
If you're looking for light cinema for an evening — this is it. If you're looking for something that'll change your perspective on life — keep scrolling.
For those who can appreciate simple pleasure without overthinking it.
Director: Bobby Farrelly
— MovieFinder Editorial
Best Watched
Viewing atmosphere: Friday evening with food and company. Doesn't require close attention — works as background too.
Chris Rock
Osmosis Jones (voice)
Laurence Fishburne
Thrax (voice)
David Hyde Pierce
Drix (voice)
Brandy Norwood
Leah (voice)
Elena Franklin
Shane Detorre
Bill Murray
Frank Detorre
William Shatner
Mayor Phlegmming (voice)
Ron Howard
Tom Colonic (voice)
Kid Rock
Kidney Rock (voice)
Molly Shannon
Mrs. Boyd
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